Talis Treatment Information
ACTEMRA
Indication
Drug Summary
ACTEMRA® is indicated for the treatment of:
-
Moderate to severe Rheumatoid Arthritis
-
Giant Cell Arteritis
-
Polyarticular Juvenile Idiopathic Arthritis
-
Systemic Juvenile Idiopathic Arthritis
-
Cytokine Release Syndrome
ACTEMRA (tocilizumab) works by helping reduce the effects of a substance in the body that can cause inflammation. It can be administered by itself or with methotrexate and other non-biologic medications. It is commonly used to treat rheumatoid arthritis.
More Information
For more information, click here to visit the manufacturer's website: www.actemra.com/
ADUHELM
Indication
ADUHELM® is indicated for the treatment of:
-
Alzheimer's Disease
Drug Summary
ADUHELM (aducanumab-avwa) is an amyloid beta-directed antibody indicated for the treatment of Alzheimer’s disease. This indication is approved under accelerated approval based on reduction in amyloid beta plaques observed in patients treated with ADUHELM.
More Information
For more information, click here to visit the manufacturer's website: www.aduhelm.com/
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AVONEX
Indication
AVONEX® is indicated for the treatment of
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Relapsing forms of multiple sclerosis (MS)
-
Clinically isolated syndrome
-
Relapsing-remitting disease
-
Active secondary progressive disease, in adults.
Drug Summary
Avonex is a brand of interferon beta-1a. Interferons are cytokines, which are proteins that cells use to communicate with each other to trigger the protective defenses of the immune system.
More Information
For more information, click here to visit the manufacturer's website: www.avonex.com
AVSOLA
Indication
AVSOLA® is indicated for the treatment of
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Adult & Pediatric Crohn's Disease
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Adult & Pediatric ulcerative colitis
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Rheumatoid Arthritis
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Ankylosing Spondylitis
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Psoriatic arthritis
-
Plaque psoriasis
Drug Summary
Avsola is proven biosimilar to Remicade and FDA approved for all Remicade indications. Avsola is indicated for reducing signs and symptoms, inducing and maintaining clinical remission and mucosal healing, and eliminating corticosteroid use in adult patients with moderately to severely active ulcerative colitis who have had an inadequate response to conventional therapy.
More Information
For more information, click here to visit the manufacturer's website: www.avsola.com
BENLYSTA
Indication
BENLYSTA® is indicated for the treatment of:
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Systemic Lupus Erythmatosus
Drug Summary
BENLYSTA (belimumab) is a biologic that reduces certain cells in your immune system, which aid in making lupus active. Adding it to other Lupus medications can maximize treatment outcomes.
More Information
For more information, click here to visit the manufacturer's website: www.benlysta.com/
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BIVIGAM
Indication
BIVIGAM® is indicated for the treatment of:
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Primary Humoral Immunodeficiency
Drug Summary
BIVIGAM (Immune Globulin Intravenous (Human), 10% Liquid) is made from healthy human blood that has a high level of certain defensive substances (antibodies), which help fight infections. It is also used to increase the blood count (platelets) in persons with a certain blood disorder (idiopathic thrombocytopenia purpura-ITP).
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CIMZIA
Indication
CIMZIA® is indicated for the treatment of:
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Crohn's Disease
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Rheumatoid Arthritis
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Psoriatic Arthritis
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Plaque Psoriasis
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Ankylosing Spondylitis
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Non-radiographic Axial Spondyloarthritis
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Adult patients who have not tolerated other medications
Drug Summary
CIMZIA (certolizumab) is a biologic medication that reduces the effects of a substance in the body causing inflammation. It is a fragment of a monoclonal antibody specific to tumor necrosis factor alpha.
More Information
For more information, click here to visit the manufacturer's website: www.cimzia.com/
Indication
CINQAIR® is indicated for the treatment of:
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Add-on maintenance treatment of patients with severe asthma aged 18 years and older, and with an eosinophilic phenotype.
Drug Summary
Cinqair (reslizumab) is a monoclonal antibody that affects the actions of the body's immune system. Reslizumab works by reducing levels of a certain type of white blood cell that may contribute to the symptoms of asthma.
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Indication
CINRYZE® is indicated for the treatment of:
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Routine prophylaxis against angioedema attacks in adults, adolescents and pediatric patients (6 years of age and older) with Hereditary Angioedema (HAE)
Drug Summary
CINRYZE® (C1 esterase inhibitor [human]) increases plasma levels of C1-INH, thereby preventing the generation of excess bradykinin to reduce the risk of a swelling attack.
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Indication
ELAPRASE® is:
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Hydrolytic lysosomal glycosaminoglycan (GAG)-specific enzyme
Drug Summary
The active substance in Elaprase, idursulfase, is a copy of the human enzyme iduronate-2-sulfatase. It replaces the enzyme that is missing or defective in patients with Hunter syndrome. Supplying the enzyme will help to break down GAGs and stop them building up in body tissue, thereby helping to improve the symptoms of the disease.
More Information
For more information, click here to visit the manufacturer's website: www.elaprase.com/
Indication
ENTIVIO® is indicated for the treatment of:
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Ulcerative Colitis
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Crohn's Disease
Drug Summary
ENTIVIO (vedolizumab) focuses on the GI tract, blocking the movement of white cells located in the gut, which helps control inflammation. It may reduce symptoms, induce and maintain remission, heal the intestinal lining or allow patients to reduce or stop the use of corticosteroids.
More Information
For more information, click here to visit the manufacturer's website: www.entivio.com/
Indication
FASENRA® is indicated for the treatment of:
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Severe eosinophilic asthma
Drug Summary
Fasenra, benralizumab, is designed to target and remove eosinophils from the blood. Fasenra is an add-on maintenance treatment for patients aged 12 and older.
More Information
For more information, click here to visit the manufacturer's website: www.fasenra.com/
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Indication
FERAHEME® is for the treatment of:
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Iron Deficiency Anemia in Adults
Drug Summary
Feraheme is in a class of medicines called iron replacement products. It works by replenishing iron so that the body can make more red blood cells that carry oxygen throughout the body.
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Indication
FERRLECIT® is for the treatment of:
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Iron Deficiency Anemia in Adults
Drug Summary
Hemoglobin carries oxygen through your blood to tissues and organs. Myoglobin helps your muscle cells store oxygen. Ferriecit is used to treat iron deficiency anemia (a lack of red blood cells caused by having too little iron in the body) in adults and children at least 6 years old.
More Information
For more information, click here to visit the manufacturer's website: Sanofi-Ferrlecit
FLEBOGAMMA
Indication
Flebogamma 10% DIF is an immune globulin intravenous (human), indicated for
treatment of:
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Primary (inherited) Immunodeficiency (PI)
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Chronic Primary Immune Thrombocytopenia (ITP) in patients 2 years of
age and older
Drug Summary
Flebogamma DIF works by restoring abnormally low IgG levels to their normal range in the blood. At higher doses, it can help to adjust an abnormal immune system and modulate the immune response.
Flebogamma DIF is made like Flebogamma, another medicine containing human normal immunoglobulin, with some additional steps in the purification of the product from human plasma.
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GAMMAGARD
Indication
GAMMAGARD is a treatment:
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Primary humoral
immunodeficiency (PI) in adult and pediatric patients two years of
age or older -
Multifocal Motor Neuropathy
Drug Summary
GAMMAGARD LIQUID is a ready-to-use liquid medicine that contains immunoglobulin G, or IgG, antibodies, which protect the body against infection. These antibodies, collected from the plasma of healthy people, replace the missing antibodies in primary immunodeficiency (PI) patients.
More Information
For more information, click here to visit the manufacturer's website: www.gammagard.com
GAMMAPLEX
Indication
GAMMAGARD is a treatment:
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Primary humoral immunodeficiency (PI) in adults and pediatric patients two
years of age and older -
Chronic immune thrombocytopenic purpura (ITP)
Drug Summary
GAMMPLEX is used to strengthen the body's natural defense system (immune system) to lower the risk of infection in persons with a weakened immune system. This medication is made from healthy human blood that has a high level of certain defensive substances (antibodies), which help fight infections. It is also used to increase the blood count (platelets) in persons with a certain blood disorder (idiopathic thrombocytopenia purpura-ITP).
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GAMMUNEX-C
Indication
GAMMUNEX-C is a treatment:
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Primary Humoral Immunodeficiency (PI) in patients 2 years of age and older
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Idiopathic Thrombocytopenic Purpura (ITP)
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Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Drug Summary
Treatment with GAMUNEX-C provides healthy antibodies to block the immune and inflammatory processes that attack and destroy myelin.
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GLASSIA
Indication
GLASSIA is a treatment:
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Emphysema due to congenital deficiency of alpha-1-proteinase inhibitor (Alpha1-PI), also known as alpha1-antitrypsin
Drug Summary
GLASSIA increases antigenic and functional (anti-neutrophil elastase capacity, ANEC) serum levels and antigenic lung epithelial lining fluid levels of Alpha1 -PI.
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INFED
Indication
INFED is a treatment for:
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Documented iron deficiency
Drug Summary
INFeD (iron dextran injection USP) is a dark brown, slightly viscous sterile liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use.
More Information
For more information, click here to visit the manufacturer's website: Infed
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INFLECTRA
Indication
INFLECTRA is a treatment for:
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Rheumatoid arthritis
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Adult ulcerative colitis
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Plaque psoriasis
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Psoriatic arthritis
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Ankylosing spondylitis
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Adult and pediatric Crohn’s disease.
Drug Summary
INFLECTRA is indicated for reducing signs and symptoms, inducing and maintaining clinical remission and mucosal healing, and eliminating corticosteroid use in adult patients with moderately to severely active ulcerative colitis who have had an inadequate response to conventional therapy.
More Information
For more information, click here to visit the manufacturer's website: Inflectra
INJECTAFER
Indication
INJECTAFER is a treatment for:
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Iron Deficiency Anemia
Drug Summary
Injectafer is indicated for the treatment of iron deficiency anemia in adult patients: who have intolerance to oral iron or have had unsatisfactory response to oral iron;
• who have non-dialysis dependent chronic kidney disease.
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IVIG
Indication
IVIg is indicated for the treatment of:
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Autoimmune Disorders
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Lupus
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Myositis
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Guillain-Barre Syndrome
-
-
Immunodeficiencies
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Idiopathic Diseases
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Kawasaki Disease
-
-
Neurological Diseases
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Myasthenia Gravis
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Multiple Sclerosis
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Chronic Inflammatory Demyelinating polyneuropathy
-
-
Infections
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Complications of organ transplants
Drug Summary
IVIg or Intravenous Immunoglobulin is sometimes administered instead of other medications, such as immunosuppressants, corticosteroids or biologic drugs to help treat immune system disorders. They are extracted from the plasma of healthy blood donors.
More Information
For more information, click here to visit website: https://www.webmd.com/a-to-z-guides/immunoglobulin-therapy
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KRYSTEXXA
Indication
KRYSTEXXA (pegloticase) is a treatment for:
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Chronic Gout
Drug Summary
KRYSTEXXA (pegloticase) is a prescription medicine used in adults to help reduce the signs and symptoms of gout that are not controlled by other treatments.
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LEQVIO
Indication
LEQVIO® (inclisiran)is a treatment for:
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Familial Hypercholesterolemia
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Family History of Familial Hypercholesterolemia
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Lowering bad cholesterol (LDL-C) in people with heart disease on a statin
Drug Summary
LEQVIO® (inclisiran) is an injectable prescription medicine used along with diet and other lipid-lowering medicines in adults who need additional lowering of "bad" cholesterol
(LDL-C) and have known cardiovascular disease and/or heterozygous familial hypercholesterolemia (HeFH), an inherited condition that causes high levels of LDL-C. It is not known if LEQVIO can decrease problems related to high cholesterol, such as heart attacks or stroke.
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NUCALA
Indication
NUCALA is a treatment for:
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Severe asthma aged 6 years and older, and with an eosinophilic phenotype
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Adult patients with eosinophilic granulomatosis with polyangiitis (EGPA)
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Hypereosinophilic syndrome (HES) for ≥6 months without an identifiable non-hematologic secondary cause
Drug Summary
Nucala works to reduce the number of eosinophils in your body. These are a type of white blood cell that’s involved in causing inflammation (swelling).
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NULOJIX
Indication
NULOJIX is a treatment for:
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Prophylaxis of organ rejection in adult patients receiving a kidney transplant.
Drug Summary
The active substance in Nulojix, belatacept, is an immunosuppressant medicine. It suppresses the
activity of ‘T cells’, immune system cells that can become involved in organ rejection.
T cells must be ‘activated’ before they work. This happens when certain molecules attach to receptors
on the surface of the T cells. Belatacept has been designed to attach to two of these molecules called
CD80 and CD86. This stops them activating the T cells, helping to prevent organ rejection.
More Information
For more information, click here to visit the manufacturer's website: www.nulojix.bmscustomerconnect.com/
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OCREVUS
Indication
OCREVUS® is indicated for the treatment of:
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Multiple Sclerosis
Drug Summary
OCREVUS (ocrelizumab) is an immunosuppressive drug used in the treatment of Relapsing and Primary Multiple Sclerosis.
More Information
For more information, click here to visit the manufacturer's website: www.ocrevus.com/
OCTAGAM
Indication
OCTAGAM® is indicated for the treatment of:
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Idiopathic thrombocytopenic purpura (ITP)
-
Primary Humoral Immunodeficiency
Drug Summary
OCTAGAM [Immune Globulin Intravenous (Human)], is used to strengthen the body's natural immune system to lower the risk of infection in persons with weakened immune systems.
More Information
For more information, click here to visit the manufacturer's website: www.octagamus.com/
ORENCIA
Indication
ORENCIA® is indicated for the treatment of:
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Adult Rheumatoid Arthritis
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Polyarticular Juvenile Idiopathic Arthritis (pJIA)
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Adult Psoriatic Arthritis (PsA)
Drug Summary
ORENCIA (abatacept) prevents your body's immune system from attacking healthy tissue. It can aid patients who are not achieving relief through their current RA regimens. It is not used as a cure for any autoimmune disorder and will only treat the symptoms of the condition.
More Information
For more information, click here to visit the manufacturer's website: www.orencia.com/
PRIVIGEN
Indication
PRIVIGEN® is indicated for the treatment of:
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Primary humoral immunodeficiency (PI)
Drug Summary
Privigen helps protect the health of people with PI by supplying their immune systems with antibodies to help prevent infections. Privigen can also help improve motor function in adults with CIDP. For people 15 years and older with chronic ITP, Privigen can raise platelet counts to help prevent bleeding.
More Information
For more information, click here to visit the manufacturer's website: https://www.privigen.com/
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PROLIA
Indication
PROLIA® is indicated for the treatment of:
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Osteoporosis
Drug Summary
PROLIA (denosumab) is a human-derived antibody that inactivates the body's bone-breakdown mechanism. It is typically administered twice a year to post-menopausal women with osteoporosis and high-risk fracture, patients with osteoporosis that other treatments have failed and patients who cannot tolerate other osteoporosis treatments.
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PROLASTIN-C
Indication
PROLASTIN-C is a treatment for:
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Emphysema due to severe hereditary deficiency of Alpha1-PI (alpha1-
antitrypsin deficiency).
Drug Summary
Prolastin-C is a concentrated form of AAT that is made from blood plasma. Prolastin-C can be effective at raising the levels of AAT protein in the bloodstream of a person with AAT deficiency.1,2
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REMICADE
Indication
REMICADE® is indicated for the treatment of:
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Rheumatoid arthritis
-
Crohn's Disease
-
Ulcerative Colitis
-
Ankylosing Spondylitis
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Psoriatic Arthritis
-
Plaque Psoriasis
Drug Summary
REMICADE (infliximab) is a monoclonal antibody that works to enhance and improve the immune system.
More Information
For more information, click here to visit the manufacturer's website: www.remicade.com/
RENFLEXIS
Indication
RENFLEXIS® is indicated for the treatment of:
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Rheumatoid arthritis in combination with methotrexate
-
Adult & Pediatric Crohn's Disease
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Adult & Pediatric Ulcerative Colitis
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Ankylosing Spondylitis
-
Psoriatic Arthritis
-
Plaque Psoriasis
Drug Summary
RENFLEXIS (infliximab-abda) is a biosimilar to Remicade that can reduce the underlying cause of the inflammation that can lead to symptoms.
For patients with Chrohn's Disease, Pediatric Crohn's Disease and Pediatric Ulcerative Colitis, Renflexis may also induce and maintain remission.
For adult patients with Ulcerative Colitis, Renflexis may also induce and maintain remission, promote intestinal healing and reduce or stop the need for steroid therapy.
For patients with Rheumatoid Arthritis and Psoriatic Arthritis, Renflexis may also stop further joint damage and improve physical function.
More Information
For more information, click here to visit the manufacturer's website: www.renflexis.com/
RITUXAN
Indication
RITUXAN® is indicated for the treatment of:
-
Rheumatoid Arthritis
-
Pemphigus Vulgaris
-
GPA/MPA Vasculitis
-
Ankylosing Spondylitis
-
Psoriatic Arthritis
-
Plaque Psoriasis
Drug Summary
RITUXAN (rituximab) is a genetically engineered chimeric/human monoclonal antibody. It is used in combination with other cancer medications to treat Non-Hodgkins Lymphoma by slowing and stopping cell growth. It can also be used to treat rheumatoid arthritis by decreasing joint pain and swelling.
More Information
For more information, click here to visit the manufacturer's website: www.rituxan.com/
SAPHNELO
Indication
SAPHNELO® is indicated for the treatment of:
-
Moderate to severe systemic lupus erythmatosus (SLE), who are receiving standard treatment
Drug Summary
SAPHNELO (anifrolumab-fnia) is a monoclonal antibody infusion therapy that works by targeting type I IFN receptors
More Information
For more information, click here to visit the manufacturer's website: www.saphnelo.com/
SD GAMMAKED
Indication
SD GAMMAKED® is indicated for the treatment of:
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Primary Humoral Immunode ciency (PI) in patients 2 years of age and older
-
Idiopathic Thrombocytopenic Purpura
Chronic In ammatory Demyelinating Polyneuropathy (CIDP)
Drug Summary
SD GAMMAKED raises platelet counts and prevents bleeding in patients with ITP who are scheduled to undergo surgery. It is also designed to improve neuromuscular disability, as well as to prevent relapse of primary humoral immunodeficiency (PI) in patients who are two years of age or older.
More Information
For more information, click here to visit the manufacturer's website: www.gammaked.com/
SIMPONI ARIA
Indication
SIMPONI ARIA® is indicated for the treatment of:
-
Rheumatoid Arthritis
-
Ankylosing Spondylitis
-
Psoriatic Arthritis
-
Polyarticular Juvenile Idiopathic arthritis
Drug Summary
SIMPONI ARIA (golimumab) is an immunosuppresive drug used to treat autoimmune diseases by reducing inflammation.
More Information
For more information, click here to visit the manufacturer's website: www.simponiaria.com/
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SOLIRIS
Indication
SOLIRIS® is indicated for the treatment of:
-
Paroxysmal Nocturnal Hemoglobinuria
-
Atypical Hemolytic Uremic Syndrome
-
Generalized Myasthenia Gravis
-
Neuromyelitis Optica Spectrum Disorder
Drug Summary
SOLIRIS (eculizumab) is a monoclonal antibody in the immunosuppressive drug category used for the treatment of hemolytic blood disorders. It works by selectively slowing down the complement cascade in the human body
More Information
For more information, click here to visit the manufacturer's website: www.soliris.com/
SOLU-MEDROL
Indication
SOLU-MEDROL® is indicated for the treatment of:
-
Rheumatoid Arthritis
-
Pemphigus Vulgaris
-
GPA/MPA Vasculitis
-
Ankylosing Spondylitis
-
Psoriatic Arthritis
-
Plaque Psoriasis
Drug Summary
SOLU-MEDROL (methylprednisolone sodium succinate for injection) is part of a potent class of anti-inflammatory agents known as corticosteroids. It is used for the treatment of inflammation, severe allergies and flares of chronic illnesses.
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STELARA IV
Indication
STELARA® is indicated for the treatment of:
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Crohn's Disease
-
Psoriatic Arthritis
-
Plaque Psoriasis
Drug Summary
STELARA (ustekinubab) is an immunosuppressive drug that reduces inflammation due to various autoimmune diseases.
More Information
For more information, click here to visit the manufacturer's website: www.stelarainfo.com/
TEPEZZA
Indication
TEPEZZA® is indicated for the treatment of:
-
Thyroid Eye Disease
Drug Summary
TEPEZZA (teprotumumab-trbw) is an infusion therapy used to treat the cause of Thyroid Eye Disease and improve symptoms including eye pain, redness and swelling. Patients may experience improved visual ability, physical appearance and double-vision.
More Information
For more information, click here to visit the manufacturer's website: www.tepezza.com/
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TYSABRI
Indication
TYSABRI® is indicated for the treatment of:
-
Multiple Sclerosis
-
Crohn's Disease
Drug Summary
TYSABRI (natalizumab) works by impairing the ability of inflammatory immune cells to attach to and pass through the cell layers lining the intestines and brain/spinal cord. It is a laboratory-produced antibody and has been proven effective in treating MS symptoms while preventing relapse, vision loss and cognitive decline. It is also used to treat Crohn's Disease.
More Information
For more information, click here to visit the manufacturer's website: www.tysabri.com
UPLIZNA
Indication
UPLIZNA® is indicated for the treatment of:
-
Neuromyelitis optica spectrum disorder (NMOSD) in adult patients who are anti-aquaporin-4 (AQP4) antibody positive
Drug Summary
UPLIZNA (inebilizumab-cdon) is an antibody therapy used to reduce relapses that may lead to permanent disability.
More Information
For more information, click here to visit the manufacturer's website: www.uplizna.com/
VENOFER
Indication
VENOFER® is indicated for the treatment of:
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Gastrointestinal Conditions
-
Chronic Kidney Disease
-
Women's Health Conditions
-
Heart Failure
-
Cancer
Drug Summary
VENOFER® (iron sucrose) injection is indicated for the treatment of iron deficiency anemia in adult and pediatric (2 years and older) with chronic kidney disea
More Information
For more information, click here to visit the manufacturer's website: www.venofer.com/
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VYEPTI
Indication
VYEPTI® is indicated for the treatment of:
-
Migraine in adults
Drug Summary
VYEPTI (eptinezumab-jjmr) is a calcitonin gene-related peptide antagonist indicated for the preventive treatment of migraine in adults.
More Information
For more information, click here to visit the manufacturer's website: www.vyepti.com/
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VYVGART
Indication
VYVGART® is indicated for the treatment of:
-
Generalized Myasthenia Gravis in adult patients who are anti-acetylcholine receptor antibody (AChR) positive
Drug Summary
VYVGART (efgartigimod alfa-fcab) is an infusion therapy that reduces the level of harmful AChR antibodies that cause the symptoms of generalized myasthenia gravis.
More Information
For more information, click here to visit the manufacturer's website: www.vygart.com/
XOLAIR
Indication
XOLAIR® is indicated for the treatment of:
-
Allergic Asthma
-
Chronic Idiopathic Urticaria (UCI)
-
Nasal Polyps
Drug Summary
XOLAIR (omalizumab) is an antibody that helps decrease asthma responses in adults and children who are at least 12 years old. It is prescribed for patients not finding relief from an inhaler or corticosteroids. It is also used for conditions causing chronic hives.
More Information
For more information, click here to visit the manufacturer's website: www.xolair.com/
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